19 Years Searching for a Cure to AIDS

User .John Cochrane
Posted Date : May 7, 2014


A lot has been accomplished over the years since HIV/AIDS first was discovered. Scientists have come a long way toward finding a cure, and in the process many of those afflicted with the disease are living much longer than in the past.

It’s the incremental steps made by scientists around the world that have gotten us this far.

Critical to that research is funding. The Campbell Foundation in Fort Lauderdale, Fla., which always has encouraged early innovation, has spent the last 19 years providing grants to help plant the seeds that have led to cutting edge research around the world.

The foundation accepts proposals for one-year grants, which are vetted by a pro bono peer review board. The process is thorough and on par with reviews conducted by the National Institutes of Health.

During its 19 years in existence, The Campbell Foundation has given away almost $9 million dollars in grants to researchers around the world.

In 2013, Funders Concerned About AIDS ranked the foundation among the top HIV/AIDS funders in the country.

Just after the start of 2014, the Campbell Foundation awarded its first grant of the year to the White River Junction VA Medical Center in Vermont.

Researchers there developed strong preliminary data showing that HSV-2 (the herpes simplex virus) exacerbates HIV due to a molecule (CXCL9) that increases the number of HIV target cells, which in turn reduces the effectiveness of tenofovir, an otherwise effective drug used to treat HIV. It’s hoped that the nearly $80,000 grant will help researchers better understand whether by blocking CXCL9 – which is activated by the sexually transmitted virus herpes simplex virus type-2 (HSV-2) – HIV-1 infection in women can be decreased and the efficacy of tenofovir can be improved.

One of the foundation’s more recent successes has come in the form of a grant to a Lauren Sciences research team at Ben-Gurion University of the Negev in Israel. Scientists there were able to overcome the “blood brain barrier” that prevents the HIV-fighting drug tenofovir from passing into the brain to treat the neurological complications of HIV.

The blood-brain barrier exists at the shared boundary between the bloodstream and central nervous system tissues. In the early days of HIV/AIDS, patients often were afflicted with severe dementia. Even today, studies suggest that as many as half of those with HIV have some cognitive defects.

The project was hugely successful and with the one-year grant provided by The Campbell Foundation, researchers were able to show delivery of significant therapeutic quantities of tenofovir into the brain by intravenous administration, according to Lauren Sciences LLC’s Chairman and CEO Susan Rosenbaum, who recently was invited to speak about the breakthrough at the Fourth Annual Conference of the American Society for Nanomedicine in Rockville, Md.

This system of synthetic nanoscale structures dubbed “V-SmartTM technology” allows both intravenous and oral medications to pass through biological barriers and makes it possible to target exactly where the drug will be released in the brain, making it more effective and reducing unwanted side effects.

The goal is to be able to begin efficacy studies in HIV mice this year and to start clinical trials about two years after. And, if it works in humans, then we may have a new therapeutic for AIDS patients.

As the Campbell Foundation prepares for its 20-year anniversary in 2015, we hope that one day our mission is accomplished and a cure for AIDS is discovered.

Ken Rapkin is a Program Officer at the Campbell Foundation.


how i got cure from hiv

Good day to you all am very happy to write this testimony  to the whole world to see the great work of the great man named dr.ekumabor  I was down over since 4year but thank god am here to give this testimony for you all to see the great powers that is hiding on this earth I was once an HIV positive but thanks to him that help me I was going through internet looking for cure when I see this man name ekumabor I quickly email him If I can get  help to grateful surprise to me he really do according to the post I see on internet this man ask me to provide  some necessary things which he  should be able to use for my cure, I did what he say and after everything, this man told me that 45mins I will be cured, that his cure will take 45mins, after 45mins as he say I should go for test I did and I was very happy when I see my result but i don’t know how he  did it but thank god for  bring this man to me am very happy to see myself am HIV negative  you can as will get your cure on yourself  email:dr.ekumaborspellhome@hotmail.com

Thank you Dr Dele for saving my marriage and my friend's life.

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how i got my HIV cure

All these post about HERBAL MEDICINE and spell casters are scammers andfake trying to collect money all in the name of HIV cure and when youcontact them, they will be asking for your name, pictures, country, phonenumber, occupation and when you have given them all the information, theywill be asking for money. I was once suffering from HIV and i spent a lotof money going from one herbal doctor to another but they all scam and takemy money away until i came in contact with this powerful one called Dr.Zanbo who cured me from HIV with his herbal medication, after doctor Zanbohas finished preparing the herbal medicine, he asked me to send him myresidential address, so that he will send the herbal medicine to me viaD.H.L so i did. 2days later, i received the herbal medicine and i had tofollow the instructions he gave to me on how i will apply it. 2weeks lateri went to hospital for test and according to the test done by the Medicaldoctor Johnson it stated that i was cured.That was not all after two yearsi was unable to get pregnant for my husband and that became a big problem. So i had to contact him again and he sent me a concoction to drink and iwas able to conceive again.he is helping to fixed problems on:1 (HIV/aids spell)2 (you are look for a man Or woman to Marriage spell)3 (you need a Child spell)4 (Becoming a manager spell)5 (Get a job spell)6 Success or pass spell7 (Love spell)Win a difficult case in court spell and many. more.Contact he of any of these today at:(zanbospiritualhome@gmail.com)So viewers be wise and beware of fake spell casters and fake herbaldoctors, they are all over the internet trying to steal from poor people. Iwill drop you the email of this powerful herbal doctor just in case youwish to contact him for help.Zanbospiritualhome@gmail.com  or you can callhim through his mobile number +2348113245192you can email me on sylasrosemary@gmail.com

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